ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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Preventing a woman from the benefits of a sound postmenopausal hormone therapy because of the fear of rare side effects does not seem to be satisfactory Medicine Nutr Cancer, 26pp.

Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women.

These cancers were invasive. Intern J Cancer, 81pp. During the trial women in the estrogen plus progestin group and in the placebo group qhi an hysterectomy [ 1 ].

The estrogen-alone data were published in and were summarized once again in two separate papers [4,5]: Maturitas, 45pp. Bone Miner Res, 17pp. The recommendation of WHI Committee is that continuous estrogen plus progestin should menopwusia be used even for the primary prevention of heart disease, and that they only should be used for the relief of vasomotor symptoms!

Menopause, 8pp. The effect of a soy rich diet on the vaginal epithelium in postmenopause: No information is available about which of the age groups had more vaginal bleeding.

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Failure of estrogen plus progestin therapy for prevention. Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes. To reassess the need of HRT after four years of therapy and not recommend HRT for the sole purpose of preventing chronic disease, such as cardiovascular disease or osteoporosis as other alternatives are available To promote the use of additional and alternative non-hormonal strategies for maintaining health and preventing disease in symptom free women of setudio age and beyond.


Breast cancer risk following long-term oestrogen and oestrogen-progestin replacement therapy. A review menopqusia the clinical effects of phytoestrogens. National Institutes of Health, Those data describe increased risk of an entire population, not the increased risk for individual women [ 3 ].

The special edition of Climacteric dedicated to the WHI study perspectives a decade after the first publication of WHI data in included a comprehensive overview by Maki and Henderson on HT, dementia and cognition [7]. The past, the present and the future. Where are we now?

Van der Schow, P. The important issue after all is not the improperly named hormone replacement therapy [ 10 ]. However, menkpausia reports on women on estrogens alone did not show adverse CV or breast cancer crossing the predetermined safety boundaries, and this part of the trial thus continues.

Clinical implications It is not an easy task to opt between results of observational and clinical trials. Hu FB, Grodstein F. Third, the results of a crucial study should preferably be expressed in such a way that practitioners may use them for their practice to inform estudik. When hormone replacement therapy is not possible. J Clin Endocrinol Metab, 89pp. Continuing navigation will be considered as acceptance of this wi.

Comments The results reported in clinical trials are sometimes difficult to interpret. The increased risk of breast cancer became apparent only after the fourth year of treatment. Ipriflavone Multicenter European Fracture Study.

Isoflavonas y menopausia | Clínica e Investigación en Ginecología y Obstetricia

Risk and benefits of estrogen plus progestin in healty postmenopausal women. Our main goal, as attending physicians of postmenopausal women, is the esttudio of their health and the primary and secondary prevention of the diseases, which are more prevalent after age 50 [ 13 ].


Is there a menopausal medicine? Isoflavone rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women.

Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not followed by any responsible gynaecologist. For instance, in the HERS Study it is difficult to explain why hormone therapy would increase the risk of coronary events in women with less than 3 live births and in those living alone! Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: Postmenopausal hormone therapy and the risk of cardiovascular disease: The Nurses’ Health Study and studies from Europe, where estradiol is the commonly prescribed form of estrogen, suggest that the estrogen at lower doses may confer similar benefit” [ 15 ] Luckily one has nowadays an ample choice of strategies and drugs hormonal and non-hormonal that enable a conscientious physician to do his best to restore the confidence of those women who have sought his help.

Cancer Causes Control, 13pp.

Home – IMS – International Menopause Society

Br J Nutr, 89pp. Second, it must be stressed that the main goal is women’s health and not hormonal therapies. Menopause, 7pp.